Welcome to the Yang Lab! We are a neuroscience research lab located in the Tufts Medical School campus in downtown Boston, Massachusetts. Our lab focuses on understanding broad neuron to glia, especially astroglia, communication mechanisms and how the dysregulation of these communication mechanisms contributes to disease processes of various neurological diseases, including the neurodevelopmental disorder Fragile X Syndrome (FXS) and neurodegenerative diseases (Amyotrophic Lateral Sclerosis and Alzheimer’s Disease). We use a wide range of modern experimental approaches with in vitro primary cell culture and in vivo mouse models to address these questions.