Welcome to the Yang Lab!

Welcome to the Yang Lab! We are a neuroscience research lab located in the Tufts Medical School campus in downtown Boston, Massachusetts. Our lab focuses on understanding broad neuron to glia, especially astroglia, communication mechanisms and how the dysregulation of these communication mechanisms contributes to disease processes of various neurological diseases, including the neurodevelopmental disorder Fragile X Syndrome (FXS) and neurodegenerative diseases (Amyotrophic Lateral Sclerosis and Alzheimer’s Disease). We use a wide range of modern experimental approaches with in vitro primary cell culture and in vivo mouse models to address these questions.

Learn more

NEWS

6/2025: Welcome new lab technician Ashley Kim and new undergraduate students Lily Tian and Anika Sen to the lab!

6/2025: Farewell lunch for fantastic lab manager Elly Keum and M.S. student Huizhong Tan. Wish them both the best of luck for their PhD study and work in the industry!

6/2025: Congratulations to Kathryn Reynolds for receiving the Zucker Research Award!

5/2025: Welcome James Kwak, a Tufts undergraduate student, to the lab!

5/2025: Carly Reynolds presented her work at the Annual Vascular Contributions to Impaired Cognition and Dementia (VCID) conference.

5/2025: Dr. Yang was invited to give a seminar on Glial mechanisms in modulating disease pathogenesis in ALS at Van Andel Institute.

5/2025: Congratulations to Marcela Bertolio, Francesca Mowry, Rashed Alananzeh, Kathryn Reynolds, and Elly Keum for their manuscript “Glutamatergic Regulation of miRNA‐Containing Intraluminal Vesicle Trafficking and Extracellular Vesicle Secretion From Cortical Neurons” to be published in the Journal of Extracellular Vesicles!